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Cyromazine |
Chemical name: |
N-cyclopropyl-1,3,5-triazine-2,4,6-triamine |
Molecular weight: |
166.2
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Molecular formular: |
C6H10N6 |
Mode of action: |
Insect growth regulator with contact action, which interferes with moulting and pupation. When used on plants, action is systemic: applied to the leaves, it exhibits a strong translaminar effect; applied to the soil, it is taken up by the roots and translocated acropetally. |
Uses: |
Control of Diptera larvae in chicken manure by feeding to the poultry or treating the breeding sites. Also used to control flies on animals. Used as a foliar spray to control leaf miners (Liriomyza spp.) in vegetables (e.g. celery, tomatoes, lettuce), melons, mushrooms, potatoes and ornamentals, at 75-225 g/ha; also used, at 190-450 g/ha, in drench or drip irrigation. |
Physical chemistry: |
Form Colourless crystals. M.p. 224.9 °C V.p. 4.48 × 10-4 mPa (25 °C) (OECD 104) Kow logP = -0.061 (pH 7.0) (OECD 107) Henry 5.8 × 10-9 Pa m3 mol-1 (calc.) S.g./density 1.35 (20 °C) Solubility In water 13 g/l (pH 7.1, 25 °C) (OECD 105). In methanol 22, isopropanol 2.5, acetone 1.7, n-octanol 1.2, dichloromethane 0.25, toluene 0.015, hexane 0.0002 (all in g/kg, 20 °C). Stability Stable up to 310 °C. Stable to hydrolysis for 28 days at up to 70 °C. pKa 5.22, weak base |
Mmmalian toxicology: |
Oral Acute oral LD50 for rats 3387 mg/kg. Skin and eye Acute percutaneous LD50 for rats >3100 mg/kg. Mild skin irritant; non-irritating to eyes (rabbits). Inhalation LC50 (4 h) for rats >2.720 mg/l air. NOEL (2 y) for rats 300, mice 1000 mg/kg diet. ADI (JMPR) 0.02 mg/kg b.w. [1990]. Toxicity Class WHO (a.i.) U; EPA (formulation) III |
Ecotoxicology: |
Birds Acute oral LD50 for bobwhite quail 1785, Japanese quail 2338, Pekin ducks >1000, mallard ducks >2510 mg/kg. Fish LC50 (96 h) for bluegill sunfish >90, carp, catfish and rainbow trout >100 mg/l. Daphnia LC50 (48 h) >9.1 mg/l. Algae LC50 124 mg/l. Bees Non-toxic to adult honeybees (no contact action up to 5 μg/bee). Worms LC50>1000 mg/kg. Other beneficial spp. Non-toxic.
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