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Tribenuron-methyl |
| Chemical name: |
methyl 2-[[[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)methylamino]-=carbonyl]amino]sulfonyl]benzoate |
| Molecular weight: |
395.4
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| Molecular formular: |
C15H17N5O6S |
Mode of action: |
Rapidly absorbed by foliage and roots and translocated throughout the plant. Susceptible plants cease growth almost immediately after post-emergence treatment and are killed in 7-21 days. Surfactants increase the activity of tribenuron-methyl on certain broad-leaved weeds. |
Uses: |
Post-emergence control of broad-leaved weeds in spring and winter cereals, at 9-30 g/ha. |
Physical chemistry: |
Composition Tech. is >95%. Form Light brown, odourless solid. M.p. 141℃) V.p. 5.2×10-5 mPa (25℃) Kowlogp= -0.44(pH 7) Henry1.03×10-8 Pa m3 mol-1 S.g./density 1.5(25℃) Solubility In water 0.05 (pH 5), 2.04 (pH 7) (both in g/l.,20℃). In acetone 43.8, acetonitrile 54.2, carbon tetrachloride 3.12, ethyl acetate 17.5, hexane 0.028, and methanol 3.39 (all in mg/l, 25℃). Stability Stable at 45℃. On hydrolysis (45℃), stable at pH 8-10 but rapid loss at pH<7 or pH>12. Relatively unstable in most organic solvents. pKa 5 |
Mammalian toxicology: |
Oral Acute oral LD50 for rats>5000 mg/kg. Skin and eye Acute percutaneous LD50 for rabbits>2000 mg/kg. Non-irritating to skin (rabbits); mild (reversible) irritant to eyes. Mildly sensitizing to skin (guinea pig maximization test). Inhalation LC50 (4 h) for rats>5.0 mg/l air. NOEL (2 y) for rats 25 ppm diet; (18 mo) for mice 200 ppm diet (30 mg/kg b.w. daily); (1 y) for dogs 250 ppm diet (8.2 mg/kg b.w. daily); (90 d) for rats 100, for mice 500, for dogs 500 mg/kg diet. Non-teratogenic in rats at 20 mg/kg daily. ADI 0.008 mg/kg. Other Non-mutagenic in the Ames test, and negative in CHO, unscheduled DNA, in vivo cytogenetic, in vivo mouse micronucleus, and in vitro human lymphocyte assays. Toxicity class WHO (a.i.) lll (Table 5); EPA (formulation) lll EC hazard R43 |
Ecotoxicology: |
Birds Acute LD50 for bobwhite quail>2250 mg/kg. Dietary LC50 (8 d) for bobwhite quail and mallard ducks>5620 mg/kg. Fish LC50 ( 96 h) for bluegill sunfish and rainbow trout>1000 mg/l. Daphnia LC50 (48 h) for 720 mg/l (unfed), 1000 mg/l (fed). Algae EC50(120 h) for green algae and blue-green alage>11.5 ug/l. Bees LD50 for honeybees>100ug/bee. Worms LD50 for earthworms>2000 ppm. |
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